By Lawrence Kruger, Barbara E. Rodin (auth.), Ralph L. Kitchell, Howard H. Erickson (eds.)
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Additional resources for Animal Pain: Perception and Alleviation
Neurophysiological studies suggest that an endogenous analgesic system exists, which at least partly operates on dorsal horn neurons via tryptaminergic pathways. The endogenous opioids have been implicated at brain stem and/or spinal levels. Morphine, the morphine antagonist naloxone, and endogenous opioids all contribute to the elucidation of the mechanisms involved. In addition to these chemicals there is good evidence that descending inhibition can be mediated via axons containing serotonin that have cell bodies in the nucleus raphe magnus of the brain stem (19).
Cervero, and A. Iggo. Intracellular marking of identified neurones in the superficial dorsal horn of the cat spinal cord. Q. J. Exp. Physiol. 66: 211-223, 1981. Oliveras, J. , G. -M. Besson. A map of serotoninergic structures involved in stimulation producing analgesia in unrestrained freely moving cats. Brain Res. 164: 317-322, 1979. Price, D. , and R. Dubner. Neurons that subserve the sensory-discriminative aspects of pain. Pain 3: 307-338, 1977. Ranson, S. W. Unmyelinated nerve-fibers as conductors of protopathic sensation.
Pain 7: 1-14, 1979. 7. Bishop, G. , and W. M. Landau. Evidence for a double peripheral pathway for pain. Science 128: 712-713, 1958. 8. Blix, M. Experimentelle Beitrage zur Losung der Frage iiber die specifische Energie der Hautnerven. Z. Bioi. Munich 20: 141-156, 1884. 9. Bonica, J. J. Causalgia and other reflex sympathetic dystrophies. In: Advances in Pain Research and Therapy, edited by J. C. Liebeskind and D. G. Albe-Fessard. New York: Raven, 1979, vo!. 3, p. 141-166. Peripheral Mechanisms of Pain 21 10.
Animal Pain: Perception and Alleviation by Lawrence Kruger, Barbara E. Rodin (auth.), Ralph L. Kitchell, Howard H. Erickson (eds.)